Prof. Dr. Begum Rokeya
Dean, Faculty of Basic Sciences
Head, Department of Pharmacology & Research Coordinator
PhD – in Pharmacology
- Professor Department of Pharmacology, Bangladesh University of Health Sciences (BUHS)
- Professor Department of Pharmacology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM)
- Associate Professor Department of Pharmacology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM)
- Principal Research Officer Department of Pharmacology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM)
- Senior Research Officer Department of Pharmacology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM)
Administrative activities:
- Dean Faculty of Basic Sciences, Bangladesh University of Health Sciences (BUHS)
- Research Coordinator Bangladesh University of Health Sciences (BUHS)
- Director Institutional Quality Assurance Cell (IQAC), Bangladesh University of Health Sciences (BUHS)
- Razon, A.H., Alauddin, M., Farzana, N., Mazumdar, S., Amin, M.R., Tusher, M.M.H., Asrafuzzaman, M., Hasan, N., Rahman, M., Saiedullah, M. and Rokeya, B., 2024. The Intricate Mechanisms of Functional Foods Oyster Mushroom and Fenugreek on Type 2 Diabetic Animal Model. Journal of Diabetes Research, 2024(1), p.6209785.
- Rahman, M.H., Asrafuzzaman, M., Tusher, M.M.H., Mosihuzzaman, M., Khan, M.S.H., Shoeb, M. and Rokeya, B., 2023. Elucidation of anti-hyperglycemic activity of Psidium guajava L.leaves extract on streptozotocin induced neonatal diabetic Long-Evans rats. Journal of Ayurveda and Integrative Medicine, 14(5), p.100776.
- Hasan, M.M., Ahmed, M.R., Karmaker, M., Khan, M.S.H., Rokeya, B. and Asna, S.M.Z.H., 2023. Microbiological analysis in different brands of Hepato-protective liquid herbal medicines available in the Dhaka city.
- Hasan R, Begum R, Huq AO, Rahman N, Akter S, Khan SH, Islam F. Development of normal phase HPLC based method for the determination of retinyl palmitate in fortified edible oils. International Journal of Food Properties. 2023 Dec 31;26(1):24-37.
- Akter F, Alam Bhuiya NM, Hasan N, Rokeya B, Zahir Raihan S, Al Mahmud Z. Cocos nucifera endocarp extract exhibits anti-diabetic and antilipidemic activities in diabetic rat model. International Journal of Scientific Research in Dental and Medical Sciences. 2022;4(1):8-15.
- Hassan MM, Uddin S, Bhowmik A, Ashraf A, Islam MM, Rokeya B. Phytochemical screening and antidiabetic effects of fruit rind of Momordica dioica roxb. on streptozocin induced type 2 diabetic rats. Heliyon. 2022 Jan 1;8(1):e08771.
- Saleh F, Banik PC, Rokeya B, Mian MA, Sultana N, Rahim AT. Assessment of quality of life (QoL) among postmenopausal women in Mohammadpur Geneva camp, Dhaka, Bangladesh using modified menopause rating scale (MRS) tool: A cross-sectional study. 2022.
- Ferdous RN, Nebir SS, Das PK, Prova AH, Moniruzzaman M, Khan MS, Rokeya B, Asna SM. Antimicrobial activity of Lannea coromandelica bark extracts against methicillin-resistant Staphylococcus aureus. BIRDEM Medical Journal. 2022 Sep 11;12(3):201-6.
- Rahman MH, Rokeya B, Mosihuzzaman M, Khan MS. Qualitative Assessment of a Customized Anti-hepatic Herbal Formulation in Bangladesh. Dhaka University Journal of Pharmaceutical Sciences. 2022 Jun 26;21(1):59-67.
- Gazi, M.S., Hossain, K.M., Rokeya, B., Barai, P. and Al Mazid, M.F., 2022. Effects of Probiotic Supplimente Yogurt on Neonatal Streptozotocin-induce type-2 Diabetic Rats. Khulna University Studies, pp.57-65.
- Mohiuddin M, Rokeya B, Al Shoeb MA, Kabir Y. Sodium benzoate in locally available soft drinks and its effect on DNA damage and liver function in rats. Dhaka University Journal of Biological Sciences. 2021:371-83.
- Rokeya B, Asrafuzzaman, M. Mosihuzzaman M, Nahar N (2021). Importance of natural products and their scope for future diabetic therapy. Asian J. Pharmacogn. 4(2): 23-34
Sarkar PK, Sarker UK, Farhana F, Ali MM, Islam MA, Haque MA, Ishigami K, Rokeya B, Roy B. Isolation and characterization of anti-diabetic compound from Clerodendrum infortunatum L. leaves. South African Journal of Botany. 2021 Nov 1;142:380-90. - Afrin F, Hossain MS, Amin MT, Islam MM, Rokeya B. Soluble Dietary Fiber from Aloe Vera and Lady's Finger; Effect on Glucose Absorption in Type-2 Diabetic Model Rats. Journal of Scientific Research. 2021 May 1;13(2):669-78.
- HassanTusher MM, Asrafuzzaman M, Rahman MH, Shuvo MJ, Ali MM, Mosihuzzaman M, Rokeya B. Antidiabetic effect of grape seed (OPC 95%) powder on nSTZ-induced type 2 diabetic model rats. African Journal of Pharmacy and Pharmacology. 2021 Jun 30;15(6):109-17.
- Ali MM, Ahmed KS, Hossain H, Roy B, Rokeya B, Rahman MT, Jahan IA, Rahman MM. Total antioxidant capacity and profiling of polyphenolic compounds in jute leaves by hplc-dad. Food Res. 2021;5:343-8.
- Ahmed MR, Shamsuddin AK, Ferdous K, Sarker MJ, Jahan I, Sultana T. Assessment of knowledge about iron deficiency anemia among the adult women in selected hospitals of Dhaka City. Journal of Advances in Medicine and Medical Research. 2021 Feb 22;33(2):78-84.
- Hossain MS, Hasan MK, Shoeb M, Mamun MI, Nahar N, Ali L, Mosihuzzaman M, Rokeya B, Chaudhury HS. Antidiabetic Activity of Momordica charantia L. and Mechanism of Insulin Scretion of 1-Butanol Soluble Part on Type 2 Diabetic Model Rats. Dhaka University Journal of Pharmaceutical Sciences. 2020 Dec 10;19(2):111-7.
- Ali MM, Asrafuzzaman M, Tusher MM, Rahman MH, Rahman MT, Roy B, Rokeya B. Comparative study on antidiabetic effect of ethanolic extract of jute leaf on neonatal streptozotocin-induced type-2 diabetic model rat. Journal of Pharmaceutical Research International. 2020 Nov 30;32(31):60-71.
- Shakil MS, Hasan MA, Uddin MF, Islam A, Nahar A, Das H, Khan MN, Dey BP, Rokeya B, Hoque SM. In vivo toxicity studies of chitosan-coated cobalt ferrite nanocomplex for its application as MRI contrast dye. ACS Applied Bio Materials. 2020 Oct 27;3(11):7952-64.
- Hasan MN, Sabrin F, Rokeya B, Khan MS, Ahmed MU, Matondo A, Billah MM, Akter S. Glucose and lipid lowering effects of Enhydra fluctuans extract in cadmium treated normal and type-2 diabetic model rats. BMC complementary and alternative medicine. 2019 Dec;19(1):1-0.
- Saleh F, Begum R, Nahar N, Begum AA, Mosihuzzaman M, Rashid M. Determination of isoflavones from soy-milk, masoor and mung dal soups in Bangladeshi postmenopausal women. The North African Journal of Food and Nutrition Research. 2018 Oct 2;2(4):81-90.
- Asrafuzzaman M, Rahman MM, Mandal M, Marjuque M, Bhowmik A, Rokeya B, Hassan Z, Faruque MO. Oyster mushroom functions as an anti-hyperglycaemic through phosphorylation of AMPK and increased expression of GLUT4 in type 2 diabetic model rats. Journal of Taibah University medical sciences. 2018 Oct 1;13(5):465-71.
- Bhowmik A, Mosihuzzaman M, Kabir Y, Rokeya B. Antihyperglycemic activity of Swertia chirata on nSTZ-T2DM rats: a chronic study. Journal of Pharmaceutical Research International. 2018 Jan 1:1-1.
22. MO F. Anti-diabetic effect of Oyster Mushroom mediates through increased AMP-activated protein kinase (AMPK) and cyclic AMP-response element binding (CREB) protein in Type 2 Diabetic model Rats. Bangladesh Journal of Medical Science. 2018 Oct 1;17(4). - Mudi SR, Akhter M, Biswas SK, Muttalib MA, Choudhury S, Rokeya B, Ali L. Effect of aqueous extract of Aegle marmelos fruit and leaf on glycemic, insulinemic and lipidemic status of type 2 diabetic model rats. Journal of Complementary and Integrative Medicine. 2017 Jun 1;14(2).
- Shahinul H Khan, Mahfuza Matin, Nasim Sultana, M Mosihuzzaman, Liaquat Ali, Begum Rokeya, A K Azad Khan, Mohammad Shoeb and Nilufar Nahar. Hypoglycemic activity of Scoparia dulcis linn extract and isolation of flavonoid glycosides. Journal of Bangladesh Chemical Society, Vol. 28(1&2), 36-47, 2016
Md Ranzu Ahmed, Ismet Ara Jahan, Khondokar Shahin Ahmed, M Abu Sayeed, Begum Rokeya, AK Azad Khan and M Mosihuzzaman. Antioxidant activity of seven antidiabetic herbal preparations available in Bangladesh. Journal of Bangladesh Chemical Society, Vol. 28(1&2), 1-8, 2016. - Uddin S, Islam MM, Hassan MM, Bhowmik A, Rokeya B. Amaranthus viridis modulates anti-hyperglycemic pathways in hemi-diaphragm and improves glycogenesis liver function in rats. Journal of Pharmacognosy and Phytotherapy. 2016 Oct 31;8(10):173-81.
- Bhowmik A, Mossihuzzaman M, Kabir Y, Rokeya B. Glycemic, Insulinemic, Lipidemic and Antioxidant Status of nSTZ Rats after Chronic Administration of Cicer arietinum Extract. Metabolomics (Los Angel). 2016;6(179):2153-0769.
- Ahmed R, Sultana T, Routary R, Khan SH, Shaari K. Chemistry and Antidiabetic Effects of Phlogocanthus thyrsiflorus Nees Flowers. Nat Prod Chem Res. 2016;4(229):2.
Ahmed MR, Asna SM, Khan MS, Rokeya B, Mosihuzzaman M, Sayeed MA. Microbial Contamination of Some Antidiabetic Herbal Preparations Available in Bangladesh. European Journal of Medicinal Plants. 2016 Jan 1;13(1):1-5. - Ahmed MR, Rokeya B, Khan AA, Zamir MR, Sayeed MA, Mosihuzzaman M. Efficacy Appraisal of Some Antidiabetic Herbal Preparations Available in Bangladesh. British Journal of Pharmaceutical Research. 2015 Jan 1;8(3).
- Hannan J, Ojo O, Rokeya L, Khaleque J, Akhter M, Flatt P, Abdel-Wahab Y. Actions underlying antidiabetic effects of Ocimum sanctum leaf extracts in animal models of type 1 and type 2 diabetes.
- Masuma Parvin, Begum Rokeya and A K Azad Chowdhury. Reporting the Clinical Trial to WHO public Registry (A service of the U.S. National Institutes of Health for registration of the clinical trial) Registration ID: Clinical Trials.gov Identifier: NCT01589445. http://clinicaltrials.gov/ct2/show/NCT01589445.
- Ansari A, Shahriar MS, Hassan MM, Das SR, Rokeya B, Haque MA, Haque ME, Biswas N, Sarkar T. Emblica officinalis improves glycemic status and oxidative stress in STZ induced type 2 diabetic model rats. Asian Pacific journal of tropical medicine. 2014 Jan 1;7(1):21-5.
- Shadli SH, Alam MO, Haque AN, Rokeya BE, Ali LI. Antihyperglycemic effect of Zingiber officinale Roscoe bark in streptozotocin-induced type 2 diabetic model rats. International Journal of Pharmacy and Pharmaceutical Sciences. 2014;6(1):711-6.
- Parvin A, Alam MM, Haque MA, Bhowmik A, Ali L, Rokeya B. Study of the hypoglycemic effect of Tamarindus indica Linn. seeds on non-diabetic and diabetic model rats. British Journal of Pharmaceutical Research. 2013 Oct 1;3(4):1094-105.
- Amrita Bhowmik, liakot Ali Khan, and Begum Rokeya: Antidiabetic effects of Mangifera indica on diabetic rat models. LAMBERT Academic publications, Saarbrucken, Germany, 2013.
- Bharati L, Amatya S, Rokeya B, Bhoumik A, Gharti KP. Study on hypoglycemic effect of Berberis aristata on type 2 diabetic model rats. Journal of Institute of Medicine. 2013 Dec 29;36(1).
- Rahman MM, Rokeya B, Shahjahan M, Ahmed T, Roy SK, Ali L. Hypoglycemic Effect of Nyctanthes arbortristis Linn Extracts in Normal and Streptozotocin-Induced Diabetic Rats. Malaysian Journal of Pharmaceutical Sciences. 2013;11(1):21.
- Akhand RN, Ahmed S, Bhowmik A, Rokeya B. Sub-chronic oral administration of the ethanolic extracts of dried Terminalia chebula mature fruits in streptozotocin (STZ)-induced type 2 diabetes mellitus (T2DM) model of Long-Evans (LE) rats improve glycemic, lipidemic and anti-oxidative status. Journal of Applied Pharmaceutical Science. 2013 May 30;3(5):027-32.
- SJ Hossain, MH Basar, B Rokeya, KMT Arif, MS Sultana and MH Rahman. Evaluation of antioxidant, antidiabetic and antibacterial activities of the fruit of Sonneratia apetala (buch.-ham.), Oriental Pharmacy and Experimental Medicine, 2013; V 13(2): 95-102, DOI 10.1007/s13596-012-0064-4.
- Moniruzzaman M, Rokeya B, Ahmed S, Bhowmik A, Khalil MI, Gan SH. In vitro antioxidant effects of Aloe barbadensis Miller extracts and the potential role of these extracts as antidiabetic and antilipidemic agents on streptozotocin-induced type 2 diabetic model rats. Molecules. 2012 Nov 1;17(11):12851-67.
- Hossain MS, Sokeng S, Shoeb M, Hasan K, Mosihuzzaman M, Nahar N, Ali L, Rokeya B. Hypoglycemic effect of Irvingia gabonensis (Aubry-Lacomate Ex. Ororke), Baill in type 2 diabetic long-evans rats. Dhaka University Journal of Pharmaceutical Sciences. 2012 Nov 4;11(1):19-24.
- Morshedul Alam, Md Anwarul Haque and Begum Rokeya. Hypoglycemic effect of Terminalia arjuna on type 2 diabetic rats. LAMBERT Academic publications, 2012.
M Parvin, AK Azad Chowdhury and B Rokeya. Pioglitazone-Metformin: Pioglitazone effects on PPAR-y variant: LAMBERT Academic publications, 2012. - Rahman MM, Haque SS, Rokeya B, Siddique MA, Banerjee SK, Ahsan SA, Rahman F, Mahmood M, Ahmed K, Bhuiyan MM, Joarder AI. Trimetazidine in the prevention of contrast induced nephropathy after coronary angiogram. Mymensingh medical journal: MMJ. 2012 Apr 1;21(2):292-9.
- Morshed MA, Fayzunnessa N, Haque MA, Uddin A, Bhoumik A, Ali L, Rokeya B. Comparative study of Azadirachta indica leaf powder and its different extracts on glycemic, insulinemic and lipidemic status of type 2 diabetic model rats. International Journal of Pharmaceutical Sciences and Research. 2011 Apr 1;2(4):954-60.
- Morshed MA, Alam J, Das M, Haque A, Ali L, Rokeya B. Antidiabetic and anti-inflammatory activity of Utica dioica leaves on stz induced type 1 diabetic model rats. International journal of pharmaceutical sciences and research. 2011 May 1;2(5):1182.
- Siddique R, Hafiz MG, Rokeya B, and Jamal CY and Islam A: Ondansetron versus granisetron in the prevention of chemotherapy induced nausea and vomiting in children with acute Lymphoblastic Leukemia.: Mymensing Med J., 2011, 20 : 4.680-688.
- Das M, Sarma BP, Rokeya B, Parial R, Nahar N, Mosihuzzaman M, Khan A, Ali L. Antihyperglycemic and antihyperlipidemic activity of Urtica dioica on type 2 diabetic model rats. J Diabetol. 2011 Jun;2(2):1-6.
- Thushari B, Begum R, Sagarika E, Liaqua A, Errol JR. Effects of Gymnema lactiferum leaf on serum glucose and cholesterol levels of streptozotocin induced diabetic rats. International Journal of Biological and Chemical Sciences. 2010;4(3).
- Bhuyan ZA, Rokeya B, Masum N, Hossain S, Mahmud I. Antidiabetic effect of Syzygium cumini L. seed on type 2 diabetic rats. Dhaka University Journal of Biological Sciences. 2010;19(2):157-64.
- Das M, Sarma BP, Khan AK, Mosihuzzaman M, Nahar N, Ali L, Bhoumik A, Rokeya B. The antidiabetic and antilipidemic activity of aqueous extract of Urtica dioica L. on type2 diabetic model rats. Journal of Bio-Science. 2009;17:1-6.
- Bandara T, Rokeya B, Khan S, Ali L, Ekanayake S, Jansz ER, Balasubramanium K. Effects of Gymnema lactiferum leaf on glycemic and lipidemic status in type 2 diabetic subjects. ||| Bangladesh Journal of Pharmacology|||. 2009;4(2):92-5.
- Bhowmik A, Khan LA, Akhter M, Rokeya B. Studies on the antidiabetic effects of Mangifera indica stem-barks and leaves on nondiabetic, type 1 and 2 diabetic model rats. ||| Bangladesh Journal of Pharmacology|||. 2009 May 20;4(2):110-4.
- Jahan IA, Nahar N, Mosihuzzaman M, Rokeya B, Ali L, Azad Khan AK, Makhmur T, Iqbal Choudhary M. Hypoglycaemic and antioxidant activities of Ficus racemosa Linn. fruits. Natural product research. 2009 Mar 10;23(4):399-408.
- Hannan JM, Ali L, Rokeya B, Khaleque J, Akhter M, Flatt PR, Abdel-Wahab YH. Soluble dietary fibre fraction of Trigonella foenum-graecum (fenugreek) seed improves glucose homeostasis in animal models of type 1 and type 2 diabetes by delaying carbohydrate digestion and absorption, and enhancing insulin action. British Journal of Nutrition. 2007 Mar;97(3):514-21.
- Sarma S, Sarma BP, Khan S, Rokeya B, Nahar N, Mosihuzzaman M, Ali L. Antidiabetic effect of Murraya koenigii leave extract on non-diabetic and diabetic model Rats. The Journal of Research and Education in Indian Medicine. 2007 Jan:43-6.
- Sokeng SD, Rokeya B, Hannan JM, Junaida K, Zitech P, Ali L, Ngounou G, Lontsi D, Kamtchouing P. Inhibitory effect of Ipomoea aquatica extracts on glucose absorption using a perfused rat intestinal preparation. Fitoterapia. 2007 Dec 1;78(7-8):526-9.
- Hannan JM, Marenah L, Ali L, Rokeya B, Flatt PR, Abdel-Wahab YH. Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta-cells. Journal of Endocrinology. 2007 Jan 1;192(1):159-68.
- Nahar Q, Rokeya B, Al Mahmood AK, Rahman M and Ali L: Effect of a Modified Chapati on Blood Glucose and Lipid Levels in Diabetic Patients. Diab Endocr J 2007; 35(1): 25-8.
Hannan JM, Marenah L, Ali L, Rokeya B, Flatt PR, Abdel-Wahab YH. Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells. Journal of Endocrinology. 2006 Apr 1;189(1):127. - Murshed S, Rokeya B, Nahar N, Khan AA, Mosihuzzaman M, Banerjee A, Maiti S, Ali L. Hypoglycemic and hypolipidemic effect of Hemidesmus indicus root on diabetic model rats. Diabetes Research. 2005;39:15-24.
- Sokeng SD, Rokeya B, Mostafa M, Nahar N, Mosihuzzaman M, Ali L, Kamtchouing P. Antihyperglycemic effect of Bridelia ndellensis ethanol extract and fractions in streptozotocin-induced diabetic rats. African Journal of Traditional, Complementary and Alternative Medicines. 2005;2(2):94-102.
- Chakrabarti S, Biswas TK, Seal T, Rokeya B, Ali L, Khan AA, Nahar N, Mosihuzzaman M, Mukherjee B. Antidiabetic activity of Caesalpinia bonducella F. in chronic type 2 diabetic model in Long-Evans rats and evaluation of insulin secretagogue property of its fractions on isolated islets. Journal of Ethnopharmacology. 2005 Feb 10;97(1):117-22.
- Rokeya B, Ali L, KHAN A, MAMMUN M, Mosihuzzaman M, Nahar N, NUREALAM M. INSULIN RELEASING EFFECTS OF MOMORDICA-CHARANTIA FRACTIONS ON ISOLATED RAT ISLETS. InDiabetologia 1995 Aug 1 (Vol. 38, pp. A193-A193). 175 FIFTH AVE, NEW YORK, NY 10010: SPRINGER VERLAG.
- Nahar Q, Rokeya B, Al Mohamood AK, Rahman M and Ali L: Effect of a modified chapati on blood glucose and lipid levels in diabetic patients. Diab Endocr J 2004; 32(2): 29-31.
Khan SH, Mosihuzzaman M, Nahar N, Rashid MA, Rokeya B, Ali L, Azad Khan AK. Three megastigmane glycosides from the leaves of Pterospermum semisagittatum. Pharmaceutical biology. 2003 Jan 1;41(7):512-5. - Hannan JM, Rokeya B, Faruque O, Nahar N, Mosihuzzaman M, Khan AA, Ali L. Effect of soluble dietary fibre fraction of Trigonella foenum graecum on glycemic, insulinemic, lipidemic and platelet aggregation status of Type 2 diabetic model rats. Journal of ethnopharmacology. 2003 Sep 1;88(1):73-7.
- Sarker AM, Rokeya B, Ahmed M, Sultana N, Chowdhury NS, Hannan JMA, Azad Khan AK, Latif ZA: Serum fructosamine assay – a parameter of short-term glycemic control in diabetic patients. Diab & Endocr J 2002; 30(1): 17.
- MAMUN MR, Rokeya B, Chowdhury NS, Muniruzzaman M, Nahar N, Ahmed MU. Anti-hyperglycemic effect of Pterospermum acerifolium Willd. and Pterospermum semisagittatum Ham. Diabetes research. 2000;35(4):163-70.
- Alamgir M, Rokeya B, Hannan JM, Choudhuri MS. The effect of Premna integrifolia Linn.(Verbenaceae) on blood glucose in streptozotocin induced type 1 and type 2 diabetic rats. Die Pharmazie. 2001 Nov;56(11):903-4.
- Alamgir M, Rokeya B, Chowdhury NS, CHOUDHURI MK. Anti-hyperglycemic effect of aqueous extract of Ocimum sanctum Linn (Labiateae) in Type 2 diabetic model rats. Diabetes research. 2001;36(1):19-27.
- Rokeya B, Nahar N, Ali L, Hassan Z, CHOWDHURY N. Effects of five medicinal plants on blood glucose levels in nondiabetic and diabetic model rats. Diabetes research. 1999;34(5):219-28.
- Nahar N, Rokeya B, Ali L, Hassan Z, Chowdhury NS. Effects of three medicinal plants on blood glucose levels of non-diabetic and diabetic model rats. Diabetes research. 2000;35(2):41-9.
- Islam S, Ali L, Rokeya B, Manan Z, Banik NG, Azad Khan AK. Insulin secretory capacity in malnutrition related diabetic mellitus subjects. Diabetes and Endocrine Journal, 1998: 1, 18-24.
- Sarkar AM, Azad Khan AK, Latif ZA, Pathan MF, Rokeya B and Hannan JMA: Effect of physical activity and mental strain on glycemic control in NIDDM subject. Journal of the Diab Assoc Bang 1996; 24: 2, 39-45.
- Azad Khan AK, Ali L, Rokeya B: Plant materials as a source of antidiabetic agents. SSMC Bulletin 1996; 1: 1-3
Ali L, Khan AK, Hassan Z, Mosihuzzaman M, Nahar N, Nasreen T, Nur-e-Alam M, Rokeya B. Characterization of the hypoglycemic effects of Trigonella foenum graecum seed. Planta medica. 1995 Aug;61(04):358-60. - Mosihuzzaman M, Nahar N, Ali L, Rokeya B, Khan AK, Nur-E-Alam M, Nandi RP. Hypoglycemic effects of three plants from eastern Himalayan belt. Diabetes Research (Edinburgh, Scotland). 1994 Jan 1;26(3):127-38.
- Ali L, Khan AK, Mamun MI, Mosihuzzaman M, Nahar N, Nur-E-Alam M, Rokeya B. Studies on hypoglycemic effects of fruit pulp, seed, and whole plant of Momordica charantia on normal and diabetic model rats. Planta medica. 1993 Oct;59(05):408-12.
- B Rokeya: Influence of neuropeptide tuftsin and its derivatives on the metabolism of brain tissue of the animals. Summary of the PhD dissertation. 1985; -22p.
- B Rokeya, YaB Maximovitch and EA Brucev: Histochemical changes in different structures of brain by the influence of tuftsin and its anologs. Archieve of Histology, 1986; 11: 33-35.
- B Rokeya: Influence of neuropeptide tuftsin and its derivatives on the contents of nicotinamide coenzymes and activity of cytochrome-c-oxidase on the brain tissue. Ukrainian Bioche J, 1985; 57: 282-84.
- Begum R, IaB M. Effect of the neuropeptide tuftsin and its derivatives on metabolism in various structures of the brain. Farmakologiia i Toksikologiia. 1985 Mar 1;48(2):41-5.
Books/Chapters:
1. Rokeya B, Asrafuzzaman M, Rashid MT, Nawar S. The Role of Introns for the Development of Inflammation-Mediated Cancer Cells. Inflammation, ItechOpen, 2021,1-22. DOI:http://dx.doi.org/10.5772/intechopen.96754
2. Begum Rokeya, Mosihuzzaman M, Azad Khan AK, Nilufar Nahar and Ali Liaquat (2011). Emerging Challenge of Type 2 Diabetes: Prospects of Medicinal Plants, In: Recent Advances in the Pathogenesis, Prevention and Management of Type 2 Diabetes and its Complications, Mark B. Zimering, MD, PhD (Ed.), ISBN: 978-953-307-597-6.
3. Begum Rokeya: Plant Materials as a Source of Potential Antidiabetic Agents. In, Mukherjee BP & Debnath PK (editors): Diabetes Mellitus Epidemic Combat the Challenge, New Delhi, Tata AcGraw-Hill Publishing Company Limited; 2004: 73-80.
4. Begum Rokeya: Antidiabetic Chronic Effect of Aqueous Extract of Allium Sativum on Glycemic and Lipidemic Status and Platelet Aggregation in Type 2 Diabetic Model Rats. Proceedings of 10th Asian Symposium on Medicinal Plants, Spices and Other Natural Products (ASOMPS X), Dhaka; 2000: 139-142.
5. Popular Bangla Book: Plant materials in the treatment of diabetes. (" Diabetes Er Chikissay Gash Gashrar Babohar". [ First published in 2013, Dhaka, Bangladesh (Publisher: ANRAP) ]
Fellowship/ Research Grant/ Travel Grant awarded
Fellowship:
- 3 months fellowship to Medical Cell Biology Department, Uppsala University, Sweden. Fellow of the International Program in the Chemical Sciences (IPICS), Sweden from 1st April to 30th June 1993.
- Two years Senior Fellowship by the Ministry of Science & Technology, Govt of the People’s Republic of Bangladesh (1995-1997).
- Senior Fellowship by the Ministry of Science & Technology, Govt of the People’s Republic of Bangladesh (Dec 1999 to November 2001).
Research Grant:
- Effect of Zingiber officinale ethanolic extract on insulin receptor in nSTZ induced diabetic model rats, from Bangladesh Medical & Research Council, 2023
Modulatory effect of Rhus chinensis and Cinnamomum tamala on GLUT4 gene expression and screening of antioxidant activity in nSTZ induced diabetic rats, from Ministry of Science and Technology (MOST), 2022. - Effect of Zingiber officinale (Ginger) on the glycemic level through antioxidant and GLUT-4 gene expression on n-STZ induced type-2 diabetic model rats, from Bangladesh Medical & Research Council, 2021.
- Anti-diabetic and anti-obesity effects of Dillenia indica (elephant apple) fruit extracts and polyphenol in diabetic type 2 rats fed high-fat diet, from Ministry and Science and Technology (MOST), 2020
- Effect of Metformin and Atorvastatin combination vs Metformin alone on inflammatory biomarkers and insulin resistance in patients with Type 2 diabetes, from Bangladesh Medical & Research Council, 2011.
- Evaluation of Safety and Efficacy of some antidiabetic herbal products from Ministry of Science & Technology, Bangladesh, 2012.
- Determination of vitamin D status among Bangladeshi prediabetic (IFG or IGTor IGT-IFG) subjects and its relation to type 2 diabetes risks”, 2011.
- Isolation, Chemical characterization and elucidation of mechanism of action of antidiabetic activity of different extracts and fractions of Psidium guajava on nSTZ-induced T2DM rats, 2017.
- Received Research Grant from International Science Progranne, Uppsala University, Sweden for the period 2019-2021 for ANRAP (Asian Network of Research on Antidiabetic Plants).
- Received Research Grant from International Science Progranne, Uppsala University, Sweden for the period 2022-2024 for ANRAP (Asian Network of Research on Antidiabetic Plants).
Travel Grant:
- Awarded travel and accommodation grants from Bangladesh & beyond to attend seminars, workshops in the various countries of the world starting from 1992 till date.
Major Research Projects
- Plant materials as a source of new antidiabetic drugs
- Effect of Insulin sensitizers and statins combination on inflammatory biomarkers and insulin resistance in patients with type diabetes.
- Determination of efficacy and safety of some antidiabetic herbal preparations available in Bangladesh on rat models and type 2 diabetic subjects.
- Evaluation of safety of some herbal formulations used against liver diseases on paracetamol induced hepatotoxicity in rats.
Current Research work is related with;
- Antidiabetic medicinal plants: i) Screening of plant materials from Bangladesh and neighboring countries like (India, Pakistan, Nepal, SriLanka, china etc) for their hypoglycemic/ antihyperglycemic properties in normal and diabetic model rats and also on isolated rat islets to monitor insulin secretion in vitro.
- Simulation of different diabetic rat models ( Streptozotocin is induced to adult rats for Type 1 or to neonates for Type 2, sucrose or high fat is fed to rats to get insulin resistant diabetic rat models).
- Dynamics of insulin secretion in diabetic model rats in response to plant derived fractions or compounds using pancreatic perfusion technique.
- Gastrointestinal dysfunction in diabetic rats and effects of natural products on GI functions using Gut perfusion technique
- Study of the mechanism underlying antidiabetic effect of different plant extracts using different segments of gastrointestinal tract.
- Modulation of insulin secretion (HOMA B) and insulin sensitivity (HOMA S) in Bangladeshi type 2 subjects by different insulin sensitizers.
- Determination of efficacy and safety of some antidiabetic herbal medicine available in Bangladesh on rat models and type 2 diabetic subjects.
- Acute toxicity studies of different antidiabetic herbal medicine available in Bangladesh on Swiss-Albino mice.
- Network Leader Asian Network of Research on Antidiabetic Plants (ANRAP), A Network Supported by International Science Programme (ISP), Uppsala University, Sweden.
- General Secretary Asian Network of Research on Antidiabetic Plants (ANRAP), A Network Supported by International Science Programme (ISP), Uppsala University, Sweden.
- Deputy Network Leader Network of Instrument Technical personnel and User scientists of Bangladesh (NITUB). A Network Supported by International Science Programme (ISP),Uppsala
University, Sweden - Joint Secretary Network of Instrument Technical personnel and User scientists of Bangladesh (NITUB). A Network Supported by International Science Programme (ISP), Uppsala University, Sweden
- Head Department of Pharmacology, Bangladesh University of Health Sciences (BUHS)
- Chief Research Officer Department of Pharmacology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders
- Member Animal Experimental Ethical Committee, Atomic Energy Commission, Dhaka
- Member Ethical Review Committee, Bangladesh University of Health Sciences
- Member Ethical Review Committee, Hamdard University Bangladesh
- Editorial Board member Journal of Pharmaceutical Research International
- Member International Advisory Committee of International Journal of Biological and Chemical Science